On some level, Lisa Clark has always known she was a designer. But her path was a bit more unconventional than most. Clark, who now designs clothing and textiles inspired by STEM (science, technology, engineering and math) topics, worked in several different industries, ranging from legal to interior design, before finding her current niche. But once she found that niche that combined her love for cerebral topics like science and math with her affinity for visual design, she knew it was meant to be. Clark said in an exclusive interview with Small Business Trends, \u201cI like to say that I come from a mid-brain genome,\u00a0having had a professional life that's been some years left brain-driven and others right brain.\u00a0My mother was a textile and fashion design executive\u00a0on Broadway\u00a0in Manhattan for decades, and the men in my family\u00a0were\u00a0all engineers and inventors.\u201d Clark didn\u2019t land on that niche and start her company, Thinker Collection, until she had already successfully worked in several different industries. She\u2019s worked for law firms, Fortune 500 companies and Silicon Valley startups. She also has an MBA in consumer and international marketing. But it wasn\u2019t until a shopping trip with her daughter that the idea for her current venture came to be. Clark explains, \u201cIn 2007-ish I was shopping with my daughter at\u00a0a retail store\u00a0in San Diego, trying to find fabric to design a room around her\u00a0then-current interests\u00a0in\u00a0science and math\u00a0and we found almost nothing. I stopped suddenly and said to her, 'My mom was a textile designer for decades, and I drew my first cells under a microscope in biology class in high school and they were just about perfect. \u00a0I bet I could draw this. \u00a0And if we're looking, there must be other people looking too.' And I realized that, through my years exposed to textiles and home design nationwide, I'd seen almost no textiles featuring STEM topics.\u201d Clark knew that there had to be a market for what she wanted to sell. Unfortunately, this revelation happened just at the beginning of the economic downturn. So access to funding wasn\u2019t as easy as she thought it would be. And since her designs were so intricate and colorful, she couldn\u2019t get them printed by traditional print shops. None of those things stopped her though. She turned to sites like RedBubble to produce her designs on garments in a cost effective manner. And just shortly after starting this new venture, Clark received one of the biggest opportunities of her career. She had displayed some of her designs outside a friend\u2019s retail store during San Diego\u2019s Fiesta del Sol celebration. And an audio engineer from CBS\u2019s "The Big Bang Theory" walked by and noticed the shirts and thought they\u2019d be perfect for the show. He gave his card to one of the shops\u00a0then-employees. Unfortunately, that employee didn\u2019t stick around. So, Clark had to really work to get back in touch with someone from the show. She explained, \u201cIt took the better part of a year for me to finally circle back and\u00a0find the right person at Warner Brothers, calling as many phone numbers related to the show as I could find. Finally, I found\u00a0the\u00a0show's\u00a0costume gal,\u00a0and relayed\u00a0to her\u00a0step by step the experience I'd had and she said, \u2018Send me a catalog.\u2019 I did, and days later Warner Brothers bought 16 shirts under a Letter of Intent, and star Jim Parsons has worn nine of them on 40+ episodes and ad promos from 2009 through 2015.\u201d Since then, her designs have also been featured in Entertainment Weekly Magazine and at a gift Suite at the Oscars. She also sells designs on Amazon,\u00a0Art.com,\u00a0AllPosters.com\u00a0and ArtistRising.com,\u00a0along with select Sheldon-worn designs on the CBS online store. It hasn\u2019t been an easy or conventional path to success for Clark. But she\u2019s found a way to use both sides of her brain to form a successful business. And it allows her to give back to STEM education and call attention to those topics in the process.